Nature Methods · 2013 · 944 citations · 21 references
Life SciencesGeneticsMolecular GeneticsGenetic EngineeringGenome EditingGenome EngineeringCrispr-based EngineeringCrispr-cas SystemsGuide Rna DesignTherapeutic Genome EditingC. Elegans Developmental ModelsCrispr-based Genome EngineeringCrispr-cas Genome EditingCrispr-cas9 Genome EditingCrispr-cas9 KnockoutCrispr-cas9 Mediated Knock-inHeritable Genome Editing
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A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity
Martin Jínek, Krzysztof Chylinski, Ines Fonfara et al. · Science · 2012 · 17.3K citations · Full text
Multiplex Genome Engineering Using CRISPR/Cas Systems
Le Cong, F. Ann Ran, David Cox et al. · Science · 2013 · 15.7K citations
THE GENETICS OF <i>CAENORHABDITIS ELEGANS</i>
Sydney Brenner · Genetics · 1974 · 15.5K citations · Full text
Life Sciences, Biology, Genetics +14
Enzymatic assembly of DNA molecules up to several hundred kilobases
Daniel G. Gibson, Lei Young, Ray-Yuan Chuang et al. · Nature Methods · 2009 · 10.9K citations
RNA-Guided Human Genome Engineering via Cas9
Prashant Mali, Luhan Yang, Kevin M. Esvelt et al. · Science · 2013 · 9.4K citations · Full text