Concepedia

Polymorphisms in Genes Involved in Folate Metabolism as Maternal Risk Factors for Down Syndrome

Charlotte A. Hobbs, Stephanie L. Sherman, Ping Yi, Sarah Hopkins, Claudine P. Torfs, R. Jean Hine, Marta Pogribna, Rima Rozen, S J James

The American Journal of Human Genetics · 2000 · 371 citations · 42 references

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References

42

Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

Xinsheng Nan, Huck‐Hui Ng, Colin A. Johnson et al. · Nature · 1998 · 3.4K citations

, , +16

Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription

Peter Lloyd Jones, Gert Jan C. Veenstra, Paul A. Wade et al. · Nature Genetics · 1998 · 2.7K citations

, , +10

Folate deficiency causes uracil misincorporation into human DNA and chromosome breakage: Implications for cancer and neuronal damage

Benjamin C. Blount, M. M. Mack, Carol M. Wehr et al. · Proceedings of the National Academy of Sciences · 1997 · 1.4K citations

, , +17

Chromosome instability and immunodeficiency syndrome caused by mutations in a DNA methyltransferase gene

Guoliang Xu, Timothy H. Bestor, Déborah Bourc’his et al. · Nature · 1999 · 1.2K citations

, , +16

DNA hypomethylation leads to elevated mutation rates

Richard Z. Chen, Ulf Pettersson, Caroline Beard et al. · Nature · 1998 · 954 citations

, , +13