S J James

Abnormal folate metabolism and mutation in the methylenetetrahydrofolate reductase gene may be maternal risk factors for Down syndrome

S J James, Marta Pogribna, Igor P. Pogribny et al. · American Journal of Clinical Nutrition · 1999 · 450 citations · Full text

Down Syndrome, Mendelian Disorder, Genetic Disorder +8

Polymorphisms in Genes Involved in Folate Metabolism as Maternal Risk Factors for Down Syndrome

Charlotte A. Hobbs, Stephanie L. Sherman, Ping Yi et al. · The American Journal of Human Genetics · 2000 · 370 citations · Full text

Down Syndrome, Genetic Disorder, Genetics +10

Breaks in genomic DNA and within the p53 gene are associated with hypomethylation in livers of folate/methyl-deficient rats.

Igor P. Pogribny, Alexei G. Basnakian, Bárbara Miller et al. · PubMed · 1995 · 311 citations

Dna Damage, Epigenetic Change, Genetics +17

Rates of apoptosis and proliferation vary with caloric intake and may influence incidence of spontaneous hepatoma in C57BL/6 x C3H F1 mice.

S J James, Levan Muskhelishvili · PubMed · 1994 · 131 citations

Apoptosis, Pathology, Cell Death +21

Suppression of the protein tyrosine phosphatase receptor type O gene (PTPRO) by methylation in hepatocellular carcinomas

Tasneem Motiwala, Kalpana Ghoshal, Anindita Das et al. · Oncogene · 2003 · 116 citations · Full text

Signal Transduction, Receptor Tyrosine Kinase, Liver Physiology +9