Concepedia

The Farnesyltransferase Inhibitor LB42708 Suppresses Vascular Endothelial Growth Factor-Induced Angiogenesis by Inhibiting Ras-dependent Mitogen-Activated Protein Kinase and Phosphatidylinositol 3-Kinase/Akt Signal Pathways

Yoon Kyung Choi, Hansoo Lee, Kwon‐Soo Ha, Moo‐Ho Won, Young‐Guen Kwon, Young-Myeong Kim

Molecular Pharmacology · 2010 · 30 citations · 25 references

DOI

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References

25

WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis.

Wafik S. El‐Deiry, Harper JW, O'Connor Pm et al. · PubMed · 1994 · 2K citations

, , +17

Cyclin D Expression Is Controlled Post-transcriptionally via a Phosphatidylinositol 3-Kinase/Akt-dependent Pathway

Robin C. Muise‐Helmericks, H. Leighton Grimes, Alfonso Bellacosa et al. · Journal of Biological Chemistry · 1998 · 512 citations · Full text

, , +17

Vascular Endothelial Cell Growth Factor Promotes Tyrosine Phosphorylation of Mediators of Signal Transduction That Contain SH2 Domains

Danqun Guo, Qing Jia, Ho-Yeong Song et al. · Journal of Biological Chemistry · 1995 · 481 citations · Full text

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Ras CAAX Peptidomimetic FTI-277 Selectively Blocks Oncogenic Ras Signaling by Inducing Cytoplasmic Accumulation of Inactive Ras-Raf Complexes

Edwina C. Lerner, Yimin Qian, Michelle A. Blaskovich et al. · Journal of Biological Chemistry · 1995 · 360 citations · Full text

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Antitumor activity of SCH 66336, an orally bioavailable tricyclic inhibitor of farnesyl protein transferase, in human tumor xenograft models and wap-ras transgenic mice.

Ming Liu, Matthew Bryant, Jianping Chen et al. · PubMed · 1998 · 309 citations

, , +15