Concepedia

Ras Signaling

Ras Signaling is a molecular pathway in cell biology that transmits extracellular signals through the Ras family of GTP-binding proteins to regulate intracellular processes such as proliferation, differentiation, and survival.

5.4K

Publications

476.8K

Citations

24.7K

Authors

3.2K

Institutions

Publications per year

2017–2026

717

Variants

Ras PathwayRas Signal Transduction

Parents

Publications

5.4K

Genetic Alterations during Colorectal-Tumor Development

Bert Vogelstein, Eric R. Fearon, Stanley R. Hamilton et al. · New England Journal of Medicine · 1988 · 6.8K citations

, , +14

K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions

J.M. Ostrem, Ulf Peters, Martin L. Sos et al. · Nature · 2013 · 2.5K citations · Full text

, , +14

Panitumumab–FOLFOX4 Treatment and <i>RAS</i> Mutations in Colorectal Cancer

Jean‐Yves Douillard, Kelly S. Oliner, Salvatore Siena et al. · New England Journal of Medicine · 2013 · 2.2K citations · Full text

, , +15

Activation of the Estrogen Receptor Through Phosphorylation by Mitogen-Activated Protein Kinase

Shigeaki Kato, Hideki Endoh, Yoshikazu Masuhiro et al. · Science · 1995 · 2K citations

, , +17

Mammalian Ras interacts directly with the serine/threonine kinase raf

Anne B. Vojtek, Stanley M. Hollenberg, Jonathan A. Cooper · Cell · 1993 · 2K citations

, , +14

1–5 of 5.4K

Authors

24.7K

  1. CJ
    Channing J. Der

    University of North Carolina at Chapel Hill, United States

    92 publications · 13.2K citations

    58

    h-index

  2. FM
    Frank McCormick

    University of California, San Francisco, United States

    78 publications · 12.7K citations

    50

    h-index

  3. JF
    John F. Hancock

    The University of Queensland, Australia

    48 publications · 9.3K citations

    41

    h-index

  4. DB
    Dafna Bar‐Sagi

    New York University, United States

    39 publications · 12.7K citations

    33

    h-index

  5. AW
    Alfred Wittinghofer

    Max Planck Institute of Molecular Physiology, Germany

    41 publications · 7K citations

    33

    h-index

1–5 of 24.7K

Institutions

3.2K

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    100 h-index

    480 publications

    113.8K citations

  2. Harvard University

    Cambridge, United States

    78 h-index

    598 publications

    72.9K citations

  3. National Cancer Institute

    Bethesda, United States

    70 h-index

    670 publications

    51.9K citations

  4. University of California, San Francisco

    San Francisco, United States

    66 h-index

    472 publications

    66.9K citations

  5. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    64 h-index

    437 publications

    52.1K citations

  6. National Institutes of Health

    Bethesda, United States

    55 h-index

    450 publications

    43.2K citations

  7. Inserm

    Paris, France

    53 h-index

    443 publications

    40.5K citations

  8. Dana-Farber Cancer Institute

    Boston, United States

    52 h-index

    352 publications

    48.1K citations

1–8 of 3.2K

Venues

  1. Journal of Biological Chemistry

    JBC · 617 publications · 54.5K citations

    125

    h-index

  2. Molecular and Cellular Biology

    MCB · 376 publications · 34.7K citations

    107

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 216 publications · 30.5K citations

    103

    h-index

  4. PubMed

    Repository · 361 publications · 22.2K citations

    75

    h-index

  5. Science

    76 publications · 31.4K citations

    72

    h-index

1–5