EMBO Reports · 2011 · 223 citations · 22 references
Life SciencesCell BiologyMolecular BiologyCell DivisionDna RepairDna ReplicationCellular AgingCellular SenescenceDna DamageDna Damage SignalingTelomere BiologyTelomere DysfunctionDna Damage Response PathwaysDna Damage Response SignalingP53 InactivationP53 Pathway InactivationReplicative SenescenceSenescence BiologyTelomere Damage ResponseTelomere Dna Damage Response
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The serial cultivation of human diploid cell strains
Leonard Hayflick, Paul S. Moorhead · Experimental Cell Research · 1961 · 8.4K citations
Telomeres shorten during ageing of human fibroblasts
Calvin B. Harley, A. B. Futcher, Carol W. Greider · Nature · 1990 · 5.7K citations
Education, Cell Biology, Genetics +11
A DNA damage checkpoint response in telomere-initiated senescence
Fabrizio d’Adda di Fagagna, Philip M. Reaper, Lorena Clay-Farrace et al. · Nature · 2003 · 2.8K citations
Mammalian Telomeres End in a Large Duplex Loop
Jack D. Griffith, Laurey Comeau, Soraya I. Rosenfield et al. · Cell · 1999 · 2.4K citations · Full text
TRF2 Protects Human Telomeres from End-to-End Fusions
Bas van Steensel, Agata Smogorzewska, Titia de Lange · Cell · 1998 · 1.7K citations · Full text