Concepedia

Dna Damage Response Pathways

DNA Damage Response Pathways is a coordinated signaling network that detects and transduces DNA damage signals to orchestrate cell cycle arrest, DNA repair, or apoptosis, thereby maintaining genomic integrity in response to genotoxic stress.

5.2K

Publications

363.3K

Citations

31.4K

Authors

4.1K

Institutions

Publications per year

2017–2026

2.1K

Variants

Ddr Pathways

Parents

Publications

5.2K

Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

Shideng Bao, Qiulian Wu, Roger E. McLendon et al. · Nature · 2006 · 6.4K citations

, , +16

Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies

Brian D. Lehmann, Joshua A. Bauer, Xi Chen et al. · Journal of Clinical Investigation · 2011 · 5.5K citations · Full text

, , +17

ATM and ATR Substrate Analysis Reveals Extensive Protein Networks Responsive to DNA Damage

Shuhei Matsuoka, Bryan A. Ballif, Agata Smogorzewska et al. · Science · 2007 · 3.1K citations

, , +17

DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis

Jiřina Bártková, Zuzana Hořejšı́, Karen Koed et al. · Nature · 2005 · 2.7K citations

, , +16

Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication

Raffaella Di Micco, Marzia Fumagalli, Angelo Cicalese et al. · Nature · 2006 · 1.8K citations

, , +16

1–5 of 5.2K

Authors

31.4K

  1. JC
    Junjie Chen

    The University of Texas MD Anderson Cancer Center, United States

    34 publications · 6.8K citations

    29

    h-index

  2. JB
    Jiří Bártek

    Danish Cancer Society, Denmark

    33 publications · 5.6K citations

    26

    h-index

  3. SJ
    Stephen J. Elledge

    Howard Hughes Medical Institute, United States

    27 publications · 10.1K citations

    24

    h-index

  4. FD
    Fabrizio d’Adda di Fagagna

    IFOM, Italy

    23 publications · 5.1K citations

    23

    h-index

  5. SP
    Stephen P. Jackson

    The Gurdon Institute, United Kingdom

    22 publications · 4.6K citations

    22

    h-index

1–5 of 31.4K

Institutions

4.1K

  1. Harvard University

    Cambridge, United States

    90 h-index

    751 publications

    140.2K citations

  2. Howard Hughes Medical Institute

    Chevy Chase, United States

    67 h-index

    270 publications

    110.2K citations

  3. The University of Texas MD Anderson Cancer Center

    Houston, United States

    61 h-index

    676 publications

    71.8K citations

  4. Dana-Farber Cancer Institute

    Boston, United States

    59 h-index

    456 publications

    59.2K citations

  5. National Institutes of Health

    Bethesda, United States

    55 h-index

    491 publications

    48.2K citations

  6. Inserm

    Paris, France

    52 h-index

    619 publications

    45.4K citations

  7. Centre National de la Recherche Scientifique

    Paris, France

    50 h-index

    574 publications

    41.6K citations

  8. Baylor College of Medicine

    Houston, United States

    48 h-index

    291 publications

    42.4K citations

1–8 of 4.1K

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 145 publications · 17.6K citations

    80

    h-index

  2. Journal of Biological Chemistry

    JBC · 234 publications · 19.1K citations

    77

    h-index

  3. Cancer Research

    144 publications · 11.1K citations

    66

    h-index

  4. Molecular and Cellular Biology

    MCB · 97 publications · 9.9K citations

    61

    h-index

  5. Nature Communications

    128 publications · 10.8K citations

    61

    h-index

1–5