Comparative Metabolic Capabilities and Inhibitory Profiles of CYP2D6.1, CYP2D6.10, and CYP2D6.17

Cytochrome P450 2D6 variants in a Caucasian population: allele frequencies and phenotypic consequences.

Christoph Sachse, Jürgen Brockmöller, Steffen Bauer et al. · PubMed · 1997 · 979 citations

Medicine, Genetics, Pharmacology +17

Comprehensive analysis of the genetic factors determining expression and function of hepatic CYP2D6

Ulrich M. Zanger, Joachim E. Fischer, Sebastian Raimundo et al. · Pharmacogenetics · 2001 · 268 citations

Medicine, Genetics, Pharmacology +17

Relative expression of cytochrome <i>P</i>450 isoenzymes in human liver and association with the metabolism of drugs and xenobiotics

Lesley M. Forrester, Colin J. Henderson, Michael J. Glancey et al. · Biochemical Journal · 1992 · 234 citations · Full text

Pharmacy, Pharmacology, Toxicology +14

Roles of NADPH-P450 Reductase and Apo- and Holo-Cytochrome b5 on Xenobiotic Oxidations Catalyzed by 12 Recombinant Human Cytochrome P450s Expressed in Membranes of Escherichia coli

Hiroshi Yamazaki, Mami Nakamura, Tomoko Komatsu et al. · Protein Expression and Purification · 2002 · 233 citations

Life Sciences, Biochemistry, Molecular Biology +17

Metoprolol and mephenytoin oxidation polymorphisms in Far Eastern Oriental subjects: Japanese versus mainland Chinese

Yukio Horai, Masayuki Nakano, Takashi Ishizaki et al. · Clinical Pharmacology & Therapeutics · 1989 · 219 citations

Veterinary Medicine, Pharmacology, Drug Metabolism +12