Inherited <i>NUDT15</i> Variant Is a Genetic Determinant of Mercaptopurine Intolerance in Children With Acute Lymphoblastic Leukemia - Concepedia

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Inherited <i>NUDT15</i> Variant Is a Genetic Determinant of Mercaptopurine Intolerance in Children With Acute Lymphoblastic Leukemia

DOI Full Paper Access

428

Citations

36

References

2015

Year

Jun J. Yang, Wendy Landier, Wenjian Yang, Chengcheng Liu, Lindsey Hageman, Cheng Cheng, Deqing Pei, Yanjun Chen, Kristine R. Crews, Nancy Kornegay,

Journal of Clinical Oncology

Abstract

We describe a germline variant in NUDT15 strongly associated with MP intolerance in childhood ALL, which may have implications for treatment individualization in this disease.

References

	Year	Citations

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