Deletion of <i>IKZF1</i> and Prognosis in Acute Lymphoblastic Leukemia

Charles G. Mullighan, Xiaoping Su, Jinghui Zhang, +25

New England Journal of Medicine

Gene-Expression Patterns in Drug-Resistant Acute Lymphoblastic Leukemia Cells and Response to Treatment

Amy de Haar-Holleman, Meyling Cheok, Monique L. den Boer, +10

New England Journal of Medicine

Germline genomic variants associated with childhood acute lymphoblastic leukemia

Lisa R. Treviño, Wenjian Yang, Deborah French, +10

Nature Genetics

Genetic DisorderMedicineGeneticsPathologyGermline Genomic Variants +5

Multiplex assessment of protein variant abundance by massively parallel sequencing

Kenneth A. Matreyek, Lea M. Starita, Jason J. Stephany, +13

Nature Genetics

Long-read SequencingFunctional GenomicsSequencingNext-generation SequencingGenetics +8

Inherited <i>NUDT15</i> Variant Is a Genetic Determinant of Mercaptopurine Intolerance in Children With Acute Lymphoblastic Leukemia

Jun J. Yang, Wendy Landier, Wenjian Yang, +12

Journal of Clinical Oncology

Germline Genetic Variation in an Organic Anion Transporter Polypeptide Associated With Methotrexate Pharmacokinetics and Clinical Effects

Lisa R. Treviño, Noriko Shimasaki, Wenjian Yang, +9

Journal of Clinical Oncology

Inherited GATA3 variants are associated with Ph-like childhood acute lymphoblastic leukemia and risk of relapse

Virginia Pérez-Andreu, Kathryn G. Roberts, Richard C. Harvey, +35

Nature Genetics

Hematological MalignancyGenetic DisorderMixed-phenotype Acute LeukemiaGeneticsGenetic Epidemiology +6

Association of an Inherited Genetic Variant With Vincristine-Related Peripheral Neuropathy in Children With Acute Lymphoblastic Leukemia

B Diouf, Kristine R. Crews, Glen Lew, +22

JAMA

Ancestry and pharmacogenomics of relapse in acute lymphoblastic leukemia

Jun J. Yang, Cheng Cheng, Meenakshi Devidas, +21

Nature Genetics

Hematological MalignancyMedicineGeneticsMixed-phenotype Acute LeukemiaAcute Lymphoblastic Leukemia +3

PG4KDS: A model for the clinical implementation of pre‐emptive pharmacogenetics

James M. Hoffman, Cyrine E. Haidar, Mark R. Wilkinson, +11

American Journal of Medical Genetics Part C Seminars in Medical Genetics

Preclinical TherapeuticsTranslational MedicineGenotype ResultPharmacokinetic ModelingMedicine +13