Thrina Loennechen

Molecular Diagnosis of Thiopurine S-Methyltransferase Deficiency: Genetic Basis for Azathioprine and Mercaptopurine Intolerance

Charles R. Yates, Eugene Y. Krynetski, Thrina Loennechen et al. · Annals of Internal Medicine · 1997 · 763 citations

Life Sciences, Genetics, Pharmacology +13

Thiopurine S-methyltransferase deficiency: two nucleotide transitions define the most prevalent mutant allele associated with loss of catalytic activity in Caucasians.

Hung-Liang Tai, Eugene Y. Krynetski, Charles R. Yates et al. · PubMed · 1996 · 320 citations

Life Sciences, Genetics, Molecular Genetics +15

S100A4 involvement in metastasis: deregulation of matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases in osteosarcoma cells transfected with an anti-S100A4 ribozyme.

Kristin Bjørnland, Jan Winberg, Eivind Hovig et al. · PubMed · 1999 · 169 citations

Medicine, Cancer Biology, Oncology +13

Isolation of a human thiopurine S-methyltransferase (TPMT) complementary DNA with a single nucleotide transition A719G (TPMT*3C) and its association with loss of TPMT protein and catalytic activity in humans*

Thrina Loennechen, Charles R. Yates, Michael Y. Fessing et al. · Clinical Pharmacology & Therapeutics · 1998 · 74 citations

Life Sciences, Genetics, Molecular Genetics +14

Interethnic difference in thiopurine methyltransferase activity

B. Klemetsdal, Eva Tollefsen, Thrina Loennechen et al. · Clinical Pharmacology & Therapeutics · 1992 · 71 citations

Life Sciences, Biochemistry, Genetics +14