Eugene Y. Krynetski

Molecular Diagnosis of Thiopurine S-Methyltransferase Deficiency: Genetic Basis for Azathioprine and Mercaptopurine Intolerance

Charles R. Yates, Eugene Y. Krynetski, Thrina Loennechen et al. · Annals of Internal Medicine · 1997 · 760 citations

Mercaptopurine Therapy Intolerance and Heterozygosity at the Thiopurine S-Methyltransferase Gene Locus

Mary V. Relling, M L Hancock, Gaston K. Rivera et al. · JNCI Journal of the National Cancer Institute · 1999 · 729 citations · Full text

Preponderance of Thiopurine S-Methyltransferase Deficiency and Heterozygosity Among Patients Intolerant to Mercaptopurine or Azathioprine

William E. Evans, Yuen Yi Hon, Lisa Bomgaars et al. · Journal of Clinical Oncology · 2001 · 401 citations

Thiopurine S-methyltransferase deficiency: two nucleotide transitions define the most prevalent mutant allele associated with loss of catalytic activity in Caucasians.

Hung-Liang Tai, Eugene Y. Krynetski, Charles R. Yates et al. · PubMed · 1996 · 320 citations

A single point mutation leading to loss of catalytic activity in human thiopurine S-methyltransferase.

Eugene Y. Krynetski, John D. Schuetz, A J Galpin et al. · Proceedings of the National Academy of Sciences · 1995 · 307 citations · Full text