Eugene Y. Krynetski - Concepedia

Author

Eugene Y. Krynetski

Also Known As

E Y Krynetski, E. Y. Krynetski, E.Y. Krynetski, EUGENE Y. KRYNETSKI, Eugene Krynetski, Eugene Y Krynetski, Eugene Y. Krynetski

Publications

Citations

H-Index

Concepts

All Affiliations

St. Jude Children's Research Hospital University of Tennessee Health Science Center University of Tennessee at Knoxville

About

Eugene Y. Krynetski is an author at St. Jude Children's Research Hospital specializing in medicine, natural sciences, and biochemistry.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	9	9	890
2	Natural Sciences	9	9	828
3	Biochemistry	8	8	754
4	Public Health	1	1	72
5	Allergy	1	1	262

Eugene Y. Krynetski

Publications

4.2K

Citations

H-Index

Page 1

	Year	Citations
Molecular Diagnosis of Thiopurine S-Methyltransferase Deficiency: Genetic Basis for Azathioprine and Mercaptopurine Intolerance Charles R. Yates, Eugene Y. Krynetski, Thrina Loennechen, Annals of Internal Medicine	1997	760
Mercaptopurine Therapy Intolerance and Heterozygosity at the Thiopurine S-Methyltransferase Gene Locus Mary V. Relling, M L Hancock, Gaston K. Rivera, JNCI Journal of the National Cancer Institute	1999	729
Preponderance of Thiopurine S-Methyltransferase Deficiency and Heterozygosity Among Patients Intolerant to Mercaptopurine or Azathioprine William E. Evans, Yuen Yi Hon, Lisa Bomgaars, Journal of Clinical Oncology	2001	401
Thiopurine S-methyltransferase deficiency: two nucleotide transitions define the most prevalent mutant allele associated with loss of catalytic activity in Caucasians. Hung-Liang Tai, Eugene Y. Krynetski, Charles R. Yates, PubMed	1996	320
A single point mutation leading to loss of catalytic activity in human thiopurine S-methyltransferase. Eugene Y. Krynetski, John D. Schuetz, A J Galpin, Proceedings of the National Academy of Sciences	1995	307
Enhanced proteolysis of thiopurine <i>S</i> -methyltransferase (TPMT) encoded by mutant alleles in humans ( <i>TPMT</i> ∗ <i>3</i> <i>A</i> , <i>TPMT</i> ∗ <i>2</i> ): Mechanisms for the genetic polymorphism of TPMT activity Hung-Liang Tai, Eugene Y. Krynetski, Erin G. Schuetz, Proceedings of the National Academy of Sciences GeneticsT-regulatory CellImmunologyTpmt MrnaHuman Polymorphism	1997	262
Differing contribution of thiopurine methyltransferase to mercaptopurine versus thioguanine effects in human leukemic cells. Thierry Dervieux, Javier G. Blanco, Eugene Y. Krynetski, PubMed Molecular PharmacologyTpmt+ CellsBiochemistryMedicineNatural Sciences	2001	137
Enhanced proteasomal degradation of mutant human thiopurine S-methyltransferase (TPMT) in mammalian cells Hung-Liang Tai, Michael Y. Fessing, Eric J. Bonten, Pharmacogenetics and Genomics GeneticsT-regulatory CellTpmt ProteinMutant TpmtProtein Expression	1999	118
Methylation of mercaptopurine, thioguanine, and their nucleotide metabolites by heterologously expressed human thiopurine S-methyltransferase. Eugene Y. Krynetski, Natalia F. Krynetskaia, Yuri Yanishevski, Molecular Pharmacology	1995	118
Reduced Folate Carrier Expression in Acute Lymphoblastic Leukemia: A Mechanism for Ploidy but not Lineage Differences in Methotrexate Accumulation Vladimir M. Belkov, Eugene Y. Krynetski, John D. Schuetz, Blood	1999	117

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