Concepedia

Treating Childhood Acute Lymphoblastic Leukemia without Cranial Irradiation

Ching-Hon Pui, Dario Campana, Deqing Pei, W. Paul Bowman, John T. Sandlund, Sue C. Kaste, Raul C. Ribeiro, Jeffrey E. Rubnitz, Susana C. Raimondi, Mihaela Onciu,

New England Journal of Medicine · 2009 · 1.2K citations · 39 references

DOIFull text

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Abstract

With effective risk-adjusted chemotherapy, prophylactic cranial irradiation can be safely omitted from the treatment of childhood ALL. (ClinicalTrials.gov number, NCT00137111.)

References

39

Chronic Health Conditions in Adult Survivors of Childhood Cancer

Kevin C. Oeffinger, Ann Mertens, Charles A. Sklar et al. · New England Journal of Medicine · 2006 · 3.5K citations

Medical Assessment of Adverse Health Outcomes in Long-term Survivors of Childhood Cancer

Maud M. Geenen, Mathilde C. Cardous-Ubbink, Leontien C.M. Kremer et al. · JAMA · 2007 · 859 citations

Improved outcome in childhood acute lymphoblastic leukemia despite reduced use of anthracyclines and cranial radiotherapy: results of trial ALL-BFM 90. German-Austrian-Swiss ALL-BFM Study Group.

Martin Schrappe, Alfred Reiter, Wolfgang Ludwig et al. · PubMed · 2000 · 609 citations

Risk-adjusted therapy of acute lymphoblastic leukemia can decrease treatment burden and improve survival: treatment results of 2169 unselected pediatric and adolescent patients enrolled in the trial ALL-BFM 95

Anja Möricke, Alfred Reiter, Martin Zimmermann et al. · Blood · 2008 · 601 citations · Full text

Conventional Compared with Individualized Chemotherapy for Childhood Acute Lymphoblastic Leukemia

William E. Evans, Mary V. Relling, John H. Rodman et al. · New England Journal of Medicine · 1998 · 495 citations