Pam (Protein associated with Myc) functions as an E3 Ubiquitin ligase and regulates TSC/mTOR signaling

A System for Stable Expression of Short Interfering RNAs in Mammalian Cells

Thijn R. Brummelkamp, René Bernards, Reuven Agami · Science · 2002 · 4.3K citations · Full text

Functional Genomics, Psuper Vector, Short Interfering Rnas +15

TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

Ken Inoki, Yong Li, Tianquan Zhu et al. · Nature Cell Biology · 2002 · 3K citations

Signal Transduction, Signaling Pathway, Cell Regulation +5

The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53

Martin Scheffner, Jon M. Huibregtse, Richard D. Vierstra et al. · Cell · 1993 · 2.4K citations

Hpv-16 E6, Ubiquitin-protein Ligase, Protein Function +4

Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase

Hideki Shimura, Nobutaka Hattori, Shinichiro Kubo et al. · Nature Genetics · 2000 · 2K citations

Ubiquitin-protein Ligase, Mendelian Disorder, Genetics +5

Lentivirus-delivered stable gene silencing by RNAi in primary cells

Sheila A. Stewart, Derek M. Dykxhoorn, Deborah Palliser et al. · RNA · 2003 · 1.6K citations · Full text

Viral Replication, Molecular Biology, Green Fluorescent Protein +16