Concepedia

Regulatory T Cells Reversibly Suppress Cytotoxic T Cell Function Independent of Effector Differentiation

Thorsten R. Mempel, Mikaël J. Pittet, Khashayarsha Khazaie, Wolfgang Weninger, Ralph Weissleder, Harald von Boehmer, Ulrich H. von Andrian

Immunity · 2006 · 489 citations · 45 references

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Signaling by intrathymic cytokines, not T cell antigen receptors, specifies CD8 lineage choice and promotes the differentiation of cytotoxic-lineage T cells

Jung‐Hyun Park, Stanley Adoro, Terry I. Guinter et al. · Nature Immunology · 2010 · 5.8K citations · Full text

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Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor α-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases

Shimon Sakaguchi, N Sakaguchi, M Asano et al. · The Journal of Immunology · 1995 · 5.5K citations

, , +17

Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival

Tyler J. Curiel, George Coukos, Linhua Zou et al. · Nature Medicine · 2004 · 5.1K citations

, , +16

Restoring function in exhausted CD8 T cells during chronic viral infection

Daniel L. Barber, E. John Wherry, David Masopust et al. · Nature · 2005 · 4K citations

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Intraepithelial CD8 <sup>+</sup> tumor-infiltrating lymphocytes and a high CD8 <sup>+</sup> /regulatory T cell ratio are associated with favorable prognosis in ovarian cancer

Eiichi Sato, Sara H. Olson, Jiyoung Ahn et al. · Proceedings of the National Academy of Sciences · 2005 · 2.4K citations · Full text

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