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High-Throughput Screening of Enzyme Inhibitors: Simultaneous Determination of Tight-Binding Inhibition Constants and Enzyme Concentration

Medicinal ChemistryDrug TargetBiochemistryTight-binding Inhibition ConstantsMedicineNatural SciencesBioanalysisRational Drug DesignEnzyme SpecificityProtein EngineeringEnzyme ConcentrationPharmacologyInhibitory ActivityDrug DiscoveryHigh-throughput Screening