James W. Janc

Telavancin Disrupts the Functional Integrity of the Bacterial Membrane through Targeted Interaction with the Cell Wall Precursor Lipid II

Christopher S. Lunde, Stephanie R. Hartouni, James W. Janc et al. · Antimicrobial Agents and Chemotherapy · 2009 · 170 citations · Full text

Life Sciences, Biochemistry, Microbiology +17

Design and Synthesis of Tri-Ring P₃ Benzamide-Containing Aminonitriles as Potent, Selective, Orally Effective Inhibitors of Cathepsin K

James T. Palmer, Clifford Bryant, Dan-Xiong Wang et al. · Journal of Medicinal Chemistry · 2005 · 94 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

A novel serine protease inhibition motif involving a multi-centered short hydrogen bonding network at the active site11Edited by D. Rees

B.A. Katz, Kyle Elrod, Christine Luong et al. · Journal of Molecular Biology · 2001 · 76 citations · Full text

Life Sciences, Biochemistry, Medicinal Chemistry +16

The Biosynthetic Gene Cluster for a Monocyclic β-Lactam Antibiotic, Nocardicin A

Michele Gunsior, Steven D. Breazeale, Amanda J Lind et al. · Chemistry & Biology · 2004 · 71 citations · Full text

Life Sciences, Microbiology, Molecular Biology +15

Keto-1,3,4-oxadiazoles as cathepsin K inhibitors

James T. Palmer, Bernard L. Hirschbein, Harry Cheung et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 68 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +8