James W. Janc

Telavancin Disrupts the Functional Integrity of the Bacterial Membrane through Targeted Interaction with the Cell Wall Precursor Lipid II

Christopher S. Lunde, Stephanie R. Hartouni, James W. Janc et al. · Antimicrobial Agents and Chemotherapy · 2009 · 170 citations · Full text

Design and Synthesis of Tri-Ring P₃ Benzamide-Containing Aminonitriles as Potent, Selective, Orally Effective Inhibitors of Cathepsin K

James T. Palmer, Clifford Bryant, Dan-Xiong Wang et al. · Journal of Medicinal Chemistry · 2005 · 94 citations · Full text

Pharmaceutical Science, Sclerostin, Bone Resorption +18

A novel serine protease inhibition motif involving a multi-centered short hydrogen bonding network at the active site11Edited by D. Rees

B.A. Katz, Kyle Elrod, Christine Luong et al. · Journal of Molecular Biology · 2001 · 76 citations · Full text

Protein Assembly, Biochemistry, Protein Folding +9

The Biosynthetic Gene Cluster for a Monocyclic β-Lactam Antibiotic, Nocardicin A

Michele Gunsior, Steven D. Breazeale, Amanda J Lind et al. · Chemistry & Biology · 2004 · 71 citations · Full text

Antimicrobial Drug Discovery, Antimicrobial Resistance Gene, Antibiotics +11

Engineering inhibitors highly selective for the S1 sites of Ser190 trypsin-like serine protease drug targets

B.A. Katz, Paul A. Sprengeler, Christine Luong et al. · Chemistry & Biology · 2001 · 67 citations · Full text

Protease Inhibitors, Protein Function, Drug Target +10