Concepedia

Anti-4-1BB-based immunotherapy for autoimmune diabetes: lessons from a transgenic non-obese diabetic (NOD) model

Huey‐Kang Sytwu, Wender Lin, Steve R. Roffler, Jung‐Tung Hung, Hsiang-Sheng Sung, Chi‐Hsien Wang, Tian‐Lu Cheng, Shey-Cherng Tsou, Sheng‐Chuan Hsi, Kuo‐Liang Shen

Journal of Autoimmunity · 2003 · 33 citations · 26 references

DOI

Concepts

References

26

‘Touchdown’ PCR to circumvent spurious priming during gene amplification

R.H. Don, Peter Cox, Brandon J. Wainwright et al. · Nucleic Acids Research · 1991 · 2.6K citations · Full text

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CTLA-4 can function as a negative regulator of T cell activation

Theresa L. Walunas, Deborah J. Lenschow, Christina Y. Bakker et al. · Immunity · 1994 · 2.2K citations

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Monoclonal antibodies against the 4-1BB T-cell activation molecule eradicate established tumors

Ignacio Melero, Walter W. Shuford, S A Newby et al. · Nature Medicine · 1997 · 891 citations

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4-1BB Costimulatory Signals Preferentially Induce CD8+ T Cell Proliferation and Lead to the Amplification In Vivo of Cytotoxic T Cell Responses

Walter W. Shuford, Kerry Klussman, Douglas D. Tritchler et al. · The Journal of Experimental Medicine · 1997 · 792 citations · Full text

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Cutting Edge: 4-1BB Is a Bona Fide CD8 T Cell Survival Signal

Chikara Takahashi, Robert S. Mittler, Anthony T. Vella · The Journal of Immunology · 1999 · 379 citations · Full text

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