Discovery and SAR of benzyl phenyl ethers as inhibitors of bacterial phenylalanyl-tRNA synthetase

New Class of Bacterial Phenylalanyl-tRNA Synthetase Inhibitors with High Potency and Broad-Spectrum Activity

D. Beyer, Hein‐Peter Kroll, Rainer Endermann et al. · Antimicrobial Agents and Chemotherapy · 2004 · 76 citations · Full text

A series of spirocyclic analogues as potent inhibitors of bacterial phenylalanyl- t RNA synthetases

Xiang Yu, John Finn, Jason M. Hill et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 27 citations · Full text

Medicine, Spirocyclic Analogues, Antimicrobial Chemotherapy +7

1-Amino-2-phenylethane 1-phosphonic acid: a specific competitive inhibitor of phenylalanyl-tRNA synthetase

J.W. Anderson, L. Fowden · Chemico-Biological Interactions · 1970 · 23 citations

1-Amino-2-phenylethane 1-Phosphonic Acid, Biosynthesis, Biochemistry +4

Discovery and optimisation of potent, selective, ethanolamine inhibitors of bacterial phenylalanyl tRNA synthetase

Richard L. Jarvest, Symon G. Erskine, Andrew K. Forrest et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 23 citations · Full text

Combinatorial Chemistry, Biosynthesis, Biochemistry +7

Rational protein engineering in action: The first crystal structure of a phenylalanine tRNA synthetase from Staphylococcus haemolyticus

A.G. Evdokimov, Marlene Mekel, Kim Hutchings et al. · Journal of Structural Biology · 2007 · 19 citations

Phenylalanine Trna Synthetase, Biochemistry, Protein Folding +12