Isolation and Expression of a Malassezia globosa Lipase Gene, LIP1

Yvonne M. DeAngelis, Charles W. Saunders, Kevin R. Johnstone, +16

Journal of Investigative Dermatology

Lipid AnalysisBiosynthesisEngineeringBiochemistryBiotechnology +3

Development of Orally Bioavailable Bicyclic Pyrazolones as Inhibitors of Tumor Necrosis Factor-α Production

Michael P. Clark, Steven K. Laughlin, Matthew J. Laufersweiler, +18

Journal of Medicinal Chemistry

Design and synthesis of a series of novel pyrazolopyridines as HIF 1-α prolyl hydroxylase inhibitors

Namal C. Warshakoon, Shengde Wu, Angelique Boyer, +9

Bioorganic & Medicinal Chemistry Letters

Molecular PharmacologyMedicinal ChemistryNovel PyrazolopyridinesBiochemistryMedicine +7

The development of 2-benzimidazole substituted pyrimidine based inhibitors of lymphocyte specific kinase (Lck)

M. Sabat, John C. VanRens, Matthew J. Laufersweiler, +10

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryDrug TargetBiochemistryMedicineNatural Sciences +8

A novel series of imidazo[1,2-a]pyridine derivatives as HIF-1α prolyl hydroxylase inhibitors

Namal C. Warshakoon, Shengde Wu, Angelique Boyer, +8

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryNovel SeriesBiochemistryNatural SciencesMedicine +8

Structure-based design, synthesis, and SAR evaluation of a new series of 8-hydroxyquinolines as HIF-1α prolyl hydroxylase inhibitors

Namal C. Warshakoon, Shengde Wu, Angelique Boyer, +10

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryBiochemistrySar EvaluationMedicineNatural Sciences +8

The development of new isoxazolone based inhibitors of tumor necrosis factor-alpha (TNF-α) production

Steven K. Laughlin, Michael P. Clark, Jane F. Djung, +13

Bioorganic & Medicinal Chemistry Letters

InflammationAnti-inflammatoryMedicineNew IsoxazoloneImmunology +8

Design and synthesis of novel N-sulfonyl-2-indole carboxamides as potent PPAR-γ binding agents with potential application to the treatment of osteoporosis

Corey R. Hopkins, Steven V. O’Neil, Michael C. Laufersweiler, +11

Bioorganic & Medicinal Chemistry Letters

BiochemistryMedicinePotential ApplicationNovel N-sulfonyl-2-indole CarboxamidesPharmacological Agent +5

Design and synthesis of substituted pyridine derivatives as HIF-1α prolyl hydroxylase inhibitors

Namal C. Warshakoon, Shengde Wu, Angelique Boyer, +11

Bioorganic & Medicinal Chemistry Letters

Molecular PharmacologyMedicinal ChemistryDerivative (Chemistry)BiochemistryMedicine +8

Engineering the catalytic domain of human protein tyrosine phosphatase β for structure-based drug discovery

A.G. Evdokimov, Matthew Pokross, Richard Walter, +12

Acta Crystallographica Section D Biological Crystallography