Timothy Braden

The Antagonists But Not Partial Agonists of Glucocorticoid Receptor Ligands Show Substantial Side Effect Dissociation

Xiao Hu, Sarah Du, Cansu Tunca et al. · Endocrinology · 2011 · 62 citations · Full text

Medicine, Molecular Biology, Pharmacology +17

Discovery of 3-Cyano- <i>N</i> -(3-(1-isobutyrylpiperidin-4-yl)-1-methyl-4-(trifluoromethyl)-1 <i>H</i> -pyrrolo[2,3- <i>b</i> ]pyridin-5-yl)benzamide: A Potent, Selective, and Orally Bioavailable Retinoic Acid Receptor-Related Orphan Receptor C2 Inverse Agonist

Mark E. Schnute, Mattias Wennerstål, Jennifer Alley et al. · Journal of Medicinal Chemistry · 2018 · 32 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Rational protein engineering in action: The first crystal structure of a phenylalanine tRNA synthetase from Staphylococcus haemolyticus

Marlene Mekel, Kim Hutchings, Lakshmi Narasimhan et al. · Journal of Structural Biology · 2007 · 20 citations

Life Sciences, Biochemistry, Molecular Biology +17

Discovery and SAR of benzyl phenyl ethers as inhibitors of bacterial phenylalanyl-tRNA synthetase

Justin I. Montgomery, Peter L. Toogood, Kim Hutchings et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 20 citations · Full text

Life Sciences, Biochemistry, Medicinal Chemistry +9

Discovery of potent, selective, bioavailable phosphodiesterase 2 (PDE2) inhibitors active in an osteoarthritis pain model, Part I: Transformation of selective pyrazolodiazepinone phosphodiesterase 4 (PDE4) inhibitors into selective PDE2 inhibitors

Mark S. Plummer, Joseph A. Cornicelli, Howard Roark et al. · Bioorganic & Medicinal Chemistry Letters · 2013 · 18 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17