Jennifer Alley

Discovery of a Potent and Orally Bioavailable Benzolactam-Derived Inhibitor of Polo-Like Kinase 1 (MLN0905)

Matthew O. Duffey, Tricia J. Vos, Ruth Adams et al. · Journal of Medicinal Chemistry · 2011 · 56 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14

Effects of Metalation State (Free Base, Mg, Zn, Cd) on Excited-State Energy Transfer in Diarylethyne-Linked Porphyrin Dimers

Philippe Hascoat, Sung Ik Yang, Robin K. Lammi et al. · Inorganic Chemistry · 1999 · 41 citations

Natural Sciences, Biochemistry, Chemistry +15

CDR-restricted engineering of native human scFvs creates highly stable and soluble bifunctional antibodies for subcutaneous delivery

Brian J. Fennell, Barry J. McDonnell, Amy Tam et al. · mAbs · 2013 · 34 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmaceutics +17

Discovery of 3-Cyano- <i>N</i> -(3-(1-isobutyrylpiperidin-4-yl)-1-methyl-4-(trifluoromethyl)-1 <i>H</i> -pyrrolo[2,3- <i>b</i> ]pyridin-5-yl)benzamide: A Potent, Selective, and Orally Bioavailable Retinoic Acid Receptor-Related Orphan Receptor C2 Inverse Agonist

Mark E. Schnute, Mattias Wennerstål, Jennifer Alley et al. · Journal of Medicinal Chemistry · 2018 · 32 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

A Novel C-C Chemoattractant Cytokine (Chemokine) Receptor 6 (CCR6) Antagonist (PF-07054894) Distinguishes between Homologous Chemokine Receptors, Increases Basal Circulating CCR6+ T Cells, and Ameliorates Interleukin-23-Induced Skin Inflammation

Wěi Li, Kimberly Crouse, Jennifer Alley et al. · Journal of Pharmacology and Experimental Therapeutics · 2023 · 23 citations · Full text

Life Sciences, Immunology, Pharmacology +17