Kimberly Crouse

Discovery of a JAK3-Selective Inhibitor: Functional Differentiation of JAK3-Selective Inhibition over pan-JAK or JAK1-Selective Inhibition

Jean‐Baptiste Telliez, Martin E. Dowty, Lu Wang et al. · ACS Chemical Biology · 2016 · 187 citations · Full text

Jak1 Inhibition, Immunology, Immune Regulation +30

Discovery of 3-Cyano- <i>N</i> -(3-(1-isobutyrylpiperidin-4-yl)-1-methyl-4-(trifluoromethyl)-1 <i>H</i> -pyrrolo[2,3- <i>b</i> ]pyridin-5-yl)benzamide: A Potent, Selective, and Orally Bioavailable Retinoic Acid Receptor-Related Orphan Receptor C2 Inverse Agonist

Mark E. Schnute, Mattias Wennerstål, Jennifer Alley et al. · Journal of Medicinal Chemistry · 2018 · 32 citations · Full text

A Novel C-C Chemoattractant Cytokine (Chemokine) Receptor 6 (CCR6) Antagonist (PF-07054894) Distinguishes between Homologous Chemokine Receptors, Increases Basal Circulating CCR6+ T Cells, and Ameliorates Interleukin-23-Induced Skin Inflammation

Wěi Li, Kimberly Crouse, Jennifer Alley et al. · Journal of Pharmacology and Experimental Therapeutics · 2023 · 20 citations · Full text

Structural basis for CCR6 modulation by allosteric antagonists

David Jonathan Wasilko, Brian S. Gerstenberger, Kathleen A. Farley et al. · Nature Communications · 2024 · 16 citations · Full text