Kathleen A. Farley

Delineating the role of cooperativity in the design of potent PROTACs for BTK

Adelajda Zorba, Chuong Nguyen, Yingrong Xu et al. · Proceedings of the National Academy of Sciences · 2018 · 409 citations · Full text

Engineering, Molecular Biology, Organic Chemistry +18

A New Resistance Gene, <i>linB</i> , Conferring Resistance to Lincosamides by Nucleotidylation in <i>Enterococcus faecium</i> HM1025

Bülent Bozdoğan, Latifa Berrezouga, M. S. KUO et al. · Antimicrobial Agents and Chemotherapy · 1999 · 175 citations · Full text

Klebsiella Pneumoniae, Bacteriology, Molecular Biology +21

Optimizing PK properties of cyclic peptides: the effect of side chain substitutions on permeability and clearance

Arthur C Rand, Siegfried S. F. Leung, Heather Eng et al. · MedChemComm · 2012 · 131 citations

Discovery of Cytotoxic Dolastatin 10 Analogues with N-Terminal Modifications

Andreas Maderna, Matthew Doroski, Chakrapani Subramanyam et al. · Journal of Medicinal Chemistry · 2014 · 130 citations

Nanotherapeutics, Lead Auristatin, Peptide Science +20

Integrating Intramolecular Hydrogen Bonding (IMHB) Considerations in Drug Discovery Using ΔlogP As a Tool

Marina Shalaeva, Giulia Caron, Yuriy A. Abramov et al. · Journal of Medicinal Chemistry · 2013 · 85 citations · Full text

Reliable δLogp, Drug Target, Computational δLogp +19