Indomethacin-induced gastric ulceration in rats: Ameliorative roles of<i>Spondias mombin</i>and<i>Ficus exasperata</i>

Abstract

These findings are indicative of gastroprotective and antioxidative potentials of the extracts which is also evident in the degree of % inhibition against ulceration. The available data in this study suggest that the extracts proved to be capable of ameliorating indomethacin-induced gastric ulceration and the probable mechanisms are via antioxidative and proton pump inhibition.