Reversible disruption of pericentric heterochromatin and centromere function by inhibiting deacetylases

The language of covalent histone modifications

Brian D. Strahl, C. David Allis · Nature · 2000 · 8.6K citations

Life Sciences, Biochemistry, Molecular Biology +12

Regulation of chromatin structure by site-specific histone H3 methyltransferases

Stephen Rea, Frank Eisenhaber, Dónal O’Carroll et al. · Nature · 2000 · 2.8K citations

Life Sciences, Genetics, Molecular Biology +14

Chromosome instability and immunodeficiency syndrome caused by mutations in a DNA methyltransferase gene

Guoliang Xu, Timothy H. Bestor, Déborah Bourc’his et al. · Nature · 1999 · 1.2K citations

Life Sciences, Genetics, Molecular Genetics +16

DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci

Michael R. Rountree, Kurtis E. Bachman, Stephen B. Baylin · Nature Genetics · 2000 · 1K citations

Life Sciences, Genetics, Molecular Biology +13

DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters

Keith D. Robertson, Slimane Ait‐Si‐Ali, Tomoki Yokochi et al. · Nature Genetics · 2000 · 942 citations

Life Sciences, Genetics, Molecular Biology +12