Abnormal quantity and function of regulatory T cells in peripheral blood of patients with severe aplastic anemia

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Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

Jason D. Fontenot, Marc A. Gavin, Alexander Y. Rudensky · Nature Immunology · 2003 · 7.7K citations

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Signaling by intrathymic cytokines, not T cell antigen receptors, specifies CD8 lineage choice and promotes the differentiation of cytotoxic-lineage T cells

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Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor α-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases

Shimon Sakaguchi, N Sakaguchi, M Asano et al. · The Journal of Immunology · 1995 · 5.5K citations

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CTLA-4 Control over Foxp3 ⁺ Regulatory T Cell Function

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