IL-15 and dendritic cells induce proliferation of CD4+CD25+ regulatory T cells from peripheral blood

Signaling by intrathymic cytokines, not T cell antigen receptors, specifies CD8 lineage choice and promotes the differentiation of cytotoxic-lineage T cells

Jung‐Hyun Park, Stanley Adoro, Terry I. Guinter et al. · Nature Immunology · 2010 · 5.8K citations · Full text

Autoimmune Disease, Lymphocyte Development, Adaptive Immune System +10

Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor α-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases

Shimon Sakaguchi, N Sakaguchi, M Asano et al. · The Journal of Immunology · 1995 · 5.4K citations

A function for interleukin 2 in Foxp3-expressing regulatory T cells

Jason D. Fontenot, Jeffrey P. Rasmussen, Marc A. Gavin et al. · Nature Immunology · 2005 · 1.8K citations

Inflammation, Cytokine, Interleukin 2 +11

Cloning of a T Cell Growth Factor that Interacts with the β Chain of the Interleukin-2 Receptor

Kenneth H. Grabstein, June Eisenman, Kurt Shanebeck et al. · Science · 1994 · 1.4K citations

T-regulatory Cell, Complementary Dna Clone, Immunology +19

Interleukin (IL) 15 is a novel cytokine that activates human natural killer cells via components of the IL-2 receptor.

William E. Carson, Judith G. Giri, M J Lindemann et al. · The Journal of Experimental Medicine · 1994 · 1.1K citations · Full text

Innate Immune System, Immunology, Immune Regulation +18