Concepedia

Caloric restriction attenuates Aβ-deposition in Alzheimer transgenic models

Nilay Patel, Marcia N. Gordon, Karen E. Connor, Robert A. Good, Robert W. Engelman, Jerimiah E. Mason, David Morgan, Todd E. Morgan, Caleb E. Finch

Neurobiology of Aging · 2004 · 329 citations · 24 references

DOI

Concepts

References

24

High-Level Neuronal Expression of Aβ<sub>1–42</sub>in Wild-Type Human Amyloid Protein Precursor Transgenic Mice: Synaptotoxicity without Plaque Formation

Lennart Mucke, Eliezer Masliah, Gui-Qiu Yu et al. · Journal of Neuroscience · 2000 · 1.9K citations · Full text

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Insulin-degrading enzyme regulates the levels of insulin, amyloid β-protein, and the β-amyloid precursor protein intracellular domain <i>in vivo</i>

Wesley Farris, Stefan Mansourian, Yang Chang et al. · Proceedings of the National Academy of Sciences · 2003 · 1.5K citations · Full text

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Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes

Leigh A. Holcomb, Marcia N. Gordon, Eileen McGowan et al. · Nature Medicine · 1998 · 1.4K citations

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Gene-expression profile of the ageing brain in mice

Cheol‐Koo Lee, Richard Weindruch, Tomas A. Prolla · Nature Genetics · 2000 · 1.1K citations

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Hypercholesterolemia Accelerates the Alzheimer's Amyloid Pathology in a Transgenic Mouse Model

Lorenzo M. Refolo, Miguel A. Pappolla, Brian Malester et al. · Neurobiology of Disease · 2000 · 994 citations · Full text

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