Concepedia

Cleavage of roquin and regnase-1 by the paracaspase MALT1 releases their cooperatively repressed targets to promote TH17 differentiation

Katharina M. Jeltsch, Desheng Hu, Sven Brenner, Jessica Zöller, Gitta Anne Heinz, Daniel Nagel, Katharina Vogel, Nina Rehage, Sebastian C. Warth, Stephanie L. Edelmann,

Nature Immunology · 2014 · 274 citations · 46 references

DOI

Concepts

References

46

HIF1α–dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells

Lewis Z. Shi, Ruoning Wang, Gonghua Huang et al. · The Journal of Experimental Medicine · 2011 · 1.8K citations · Full text

, , +17

Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1

Eric V. Dang, Joseph Barbi, Huang‐Yu Yang et al. · Cell · 2011 · 1.6K citations · Full text

, , +13

Defective TCR expression in transgenic mice constructed using cDNA‐based α‐ and β‐chain genes under the control of heterologous regulatory elements

Megan Barnden, Jan Allison, William R. Heath · Immunology and Cell Biology · 1998 · 1.5K citations

, , +15

A Critical Role for Dnmt1 and DNA Methylation in T Cell Development, Function, and Survival

Peggy P. Lee, David Fitzpatrick, Caroline Beard et al. · Immunity · 2001 · 1.3K citations · Full text

, , +16

A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity

Carola G. Vinuesa, Matthew Cook, Constanza Angelucci et al. · Nature · 2005 · 858 citations

, , +14