Daniel Nagel

Cleavage of roquin and regnase-1 by the paracaspase MALT1 releases their cooperatively repressed targets to promote TH17 differentiation

Katharina M. Jeltsch, Desheng Hu, Sven Brenner et al. · Nature Immunology · 2014 · 268 citations

Biology, Paracaspase Malt1, Molecular Regulation +8

Pharmacologic Inhibition of MALT1 Protease by Phenothiazines as a Therapeutic Approach for the Treatment of Aggressive ABC-DLBCL

Daniel Nagel, Stefani Spranger, Michelle Vincendeau et al. · Cancer Cell · 2012 · 227 citations · Full text

Medicinal Chemistry, Biochemistry, Pharmacologic Inhibition +8

Critical role of PI3K signaling for NF-κB–dependent survival in a subset of activated B-cell–like diffuse large B-cell lymphoma cells

Bernhard Kloo, Daniel Nagel, Matthias Pfeifer et al. · Proceedings of the National Academy of Sciences · 2010 · 147 citations · Full text

NF-κB Essential Modulator (NEMO) Interaction with Linear and Lys-63 Ubiquitin Chains Contributes to NF-κB Activation

Kamyar Hadian, Richard A. Griesbach, Scarlett Dornauer et al. · Journal of Biological Chemistry · 2011 · 107 citations · Full text

Molecular Regulation, Immunology, Immune Regulation +16

Structural Analysis of Phenothiazine Derivatives as Allosteric Inhibitors of the MALT1 Paracaspase

Florian Schlauderer, Katja Lammens, Daniel Nagel et al. · Angewandte Chemie International Edition · 2013 · 82 citations

Crystal Structure, Second Site, Immunology +21