Lewis Z. Shi

The Transcription Factor Myc Controls Metabolic Reprogramming upon T Lymphocyte Activation

Ruoning Wang, Christopher P. Dillon, Lewis Z. Shi et al. · Immunity · 2011 · 2.1K citations · Full text

Life Sciences, Immunology, Molecular Biology +12

HIF1α–dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells

Lewis Z. Shi, Ruoning Wang, Gonghua Huang et al. · The Journal of Experimental Medicine · 2011 · 1.8K citations · Full text

Life Sciences, Cell Biology, Immunology +17

Loss of IFN-γ Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy

Jianjun Gao, Lewis Z. Shi, Hao Zhao et al. · Cell · 2016 · 1.3K citations · Full text

Medicine, Immunology, Oncology +16

VISTA is an inhibitory immune checkpoint that is increased after ipilimumab therapy in patients with prostate cancer

Jianjun Gao, John F. Ward, Curtis A. Pettaway et al. · Nature Medicine · 2017 · 592 citations

Life Sciences, Immunology, Oncology +16

Interdependent IL-7 and IFN-γ signalling in T-cell controls tumour eradication by combined α-CTLA-4+α-PD-1 therapy

Lewis Z. Shi, Tihui Fu, Baoxiang Guan et al. · Nature Communications · 2016 · 112 citations · Full text

Life Sciences, Immunology, Oncology +17