Viability of freeze dried microencapsulated human retinal pigment epithelial cells

Microencapsulated Islets as Bioartificial Endocrine Pancreas

Franklin Lim, Anthony M. Sun · Science · 1980 · 2.4K citations

Engineering, Bioengineering, Biomedical Engineering +17

Trehalose and sucrose protect both membranes and proteins in intact bacteria during drying

Samuel Leslie, Eitan Israeli, Bruce Lighthart et al. · Applied and Environmental Microbiology · 1995 · 969 citations · Full text

Life Sciences, Biochemistry, Microbiology +14

Ciliary neurotrophic factor (CNTF) for human retinal degeneration: Phase I trial of CNTF delivered by encapsulated cell intraocular implants

Paul A. Sieving, Rafael C. Caruso, Weng Tao et al. · Proceedings of the National Academy of Sciences · 2006 · 592 citations · Full text

Medicine, Ophthalmology, Vision Science +10

Hydrogen Bonding between Sugar and Protein Is Responsible for Inhibition of Dehydration-Induced Protein Unfolding

Steven Allison, Byeong S. Chang, Theodore W. Randolph et al. · Archives of Biochemistry and Biophysics · 1999 · 538 citations

Life Sciences, Biochemistry, Biophysics +14

Membrane stabilization during freezing: The role of two natural cryoprotectants, trehalose and proline

Alan S. Rudolph, John H. Crowe · Cryobiology · 1985 · 426 citations

Life Sciences, Biochemistry, Biophysics +12