17-AAG, an Hsp90 inhibitor, ameliorates polyglutamine-mediated motor neuron degeneration

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A high-affinity conformation of Hsp90 confers tumour selectivity on Hsp90 inhibitors

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Repression of Heat Shock Transcription Factor HSF1 Activation by HSP90 (HSP90 Complex) that Forms a Stress-Sensitive Complex with HSF1

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Life Sciences, Genetics, Molecular Biology +14

Reversal of Neuropathology and Motor Dysfunction in a Conditional Model of Huntington's Disease

Ai Yamamoto, José J. Lucas, René Hen · Cell · 2000 · 1.1K citations · Full text

Life Sciences, Neurobiology, Neuroscience +17