Makoto Minamiyama

17-AAG, an Hsp90 inhibitor, ameliorates polyglutamine-mediated motor neuron degeneration

Masahiro Waza, Hiroaki Adachi, Masahisa Katsuno et al. · Nature Medicine · 2005 · 384 citations

Neurodegenerative Diseases, Molecular Neuroscience, Hsp90 Inhibitor +7

Leuprorelin rescues polyglutamine-dependent phenotypes in a transgenic mouse model of spinal and bulbar muscular atrophy

Masahisa Katsuno, Hiroaki Adachi, Manabu Doyu et al. · Nature Medicine · 2003 · 288 citations

Knockout Mouse, Degenerative Disease, Neuroscience +4

Sodium butyrate ameliorates phenotypic expression in a transgenic mouse model of spinal and bulbar muscular atrophy

Makoto Minamiyama · Human Molecular Genetics · 2004 · 257 citations

Knockout Mouse, Neurodegenerative Diseases, Systems Biology +15

Heat Shock Protein 70 Chaperone Overexpression Ameliorates Phenotypes of the Spinal and Bulbar Muscular Atrophy Transgenic Mouse Model by Reducing Nuclear-Localized Mutant Androgen Receptor Protein

Hiroaki Adachi, Masahisa Katsuno, Makoto Minamiyama et al. · Journal of Neuroscience · 2003 · 255 citations · Full text

Pharmacological induction of heat-shock proteins alleviates polyglutamine-mediated motor neuron disease

Masahisa Katsuno, Chen Sang, Hiroaki Adachi et al. · Proceedings of the National Academy of Sciences · 2005 · 234 citations · Full text