Testosterone Reduction Prevents Phenotypic Expression in a Transgenic Mouse Model of Spinal and Bulbar Muscular Atrophy

Masahisa Katsuno, Hiroaki Adachi, Akito Kume, +7

Neuron

Knockout MouseEndocrine MechanismGeneticsPhysiologyTransgenic Mouse Model +5

17-AAG, an Hsp90 inhibitor, ameliorates polyglutamine-mediated motor neuron degeneration

Masahiro Waza, Hiroaki Adachi, Masahisa Katsuno, +6

Nature Medicine

Neurodegenerative DiseasesMolecular NeuroscienceHsp90 InhibitorNeuroprotectionNeurology +5

Leuprorelin rescues polyglutamine-dependent phenotypes in a transgenic mouse model of spinal and bulbar muscular atrophy

Masahisa Katsuno, Hiroaki Adachi, Manabu Doyu, +5

Nature Medicine

Knockout MouseDegenerative DiseaseNeuroscienceBulbar Muscular AtrophyTransgenic Mouse Model +2

Heat Shock Protein 70 Chaperone Overexpression Ameliorates Phenotypes of the Spinal and Bulbar Muscular Atrophy Transgenic Mouse Model by Reducing Nuclear-Localized Mutant Androgen Receptor Protein

Hiroaki Adachi, Masahisa Katsuno, Makoto Minamiyama, +8

Journal of Neuroscience

Pharmacological induction of heat-shock proteins alleviates polyglutamine-mediated motor neuron disease

Masahisa Katsuno, Chen Sang, Hiroaki Adachi, +5

Proceedings of the National Academy of Sciences

Pharmaco-proteogenomic characterization of liver cancer organoids for precision oncology

Shuyi Ji, Feng Li, Zile Fu, +31

Science Translational Medicine

Tumor BiologyMedicineLiver PhysiologyHepatobiliary TumorPharmacology +10

Rapid alterations of cell cycle control proteins in human T lymphocytes in microgravity

Cora S. Thiel, Katrin Paulsen, Gesine Bradacs, +15

Cell Communication and Signaling

Influence of obesity on the early and long term results of surgery for coronary artery disease

Umesh Prasad, William F. Walker, Chen Sang, +2

European Journal of Cardio-Thoracic Surgery

Accurate segmentation of overlapping cells in cervical cytology with deep convolutional neural networks

Tao Wan, Shusong Xu, Chen Sang, +2

Neurocomputing

Cervical CytologyCell DetectionEngineeringCervical CancerMedical Imaging +11

The lncRNA ZFAS1 regulates lipogenesis in colorectal cancer by binding polyadenylate-binding protein 2 to stabilize SREBP1 mRNA

Huishan Wang, Yu‐Li Chen, Yan-wen Liu, +10

Molecular Therapy — Nucleic Acids