Gen Sobue

Safety and efficacy of edaravone in well defined patients with amyotrophic lateral sclerosis: a randomised, double-blind, placebo-controlled trial

Koji Abe, Masashi Aoki, Shoji Tsuji et al. · The Lancet Neurology · 2017 · 925 citations

Life Sciences, Neurology, Neuroscience +11

A gene encoding a transmembrane protein is mutated in patients with diabetes mellitus and optic atrophy (Wolfram syndrome)

Hiroshi Inoue, Yukio Tanizawa, P Behn et al. · Nature Genetics · 1998 · 755 citations

Medicine, Genetics, Molecular Genetics +15

A rescue factor abolishing neuronal cell death by a wide spectrum of familial Alzheimer's disease genes and Aβ

Yuichi Hashimoto, Takako Niikura, Hirohisa Tajima et al. · Proceedings of the National Academy of Sciences · 2001 · 616 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +17

The wide spectrum of clinical manifestations in Sjögren's syndrome-associated neuropathy

Keiko Mori, Masahiro Iijima, Haruki Koike et al. · Brain · 2005 · 544 citations · Full text

Medicine, Neurology, Autoimmunity +15

Long-read sequencing identifies GGC repeat expansions in NOTCH2NLC associated with neuronal intranuclear inclusion disease

Jun Sone, Satomi Mitsuhashi, Atsushi Fujita et al. · Nature Genetics · 2019 · 509 citations

Life Sciences, Molecular Genetics, Neuroscience +14