Gen Sobue

Safety and efficacy of edaravone in well defined patients with amyotrophic lateral sclerosis: a randomised, double-blind, placebo-controlled trial

Koji Abe, Masashi Aoki, Shoji Tsuji et al. · The Lancet Neurology · 2017 · 900 citations

Neurodegenerative Diseases, Amyotrophic Lateral Sclerosis, Neurological Disorder +6

A gene encoding a transmembrane protein is mutated in patients with diabetes mellitus and optic atrophy (Wolfram syndrome)

Hiroshi Inoue, Yukio Tanizawa, P Behn et al. · Nature Genetics · 1998 · 741 citations

A rescue factor abolishing neuronal cell death by a wide spectrum of familial Alzheimer's disease genes and Aβ

Yuichi Hashimoto, Takako Niikura, Hirohisa Tajima et al. · Proceedings of the National Academy of Sciences · 2001 · 603 citations · Full text

The wide spectrum of clinical manifestations in Sjögren's syndrome-associated neuropathy

Keiko Mori, Masahiro Iijima, Haruki Koike et al. · Brain · 2005 · 533 citations · Full text

Painful Sensory Neuropathy, Rheumatology, Autoimmune Disease +12

Long-read sequencing identifies GGC repeat expansions in NOTCH2NLC associated with neuronal intranuclear inclusion disease

Jun Sone, Satomi Mitsuhashi, Atsushi Fujita et al. · Nature Genetics · 2019 · 479 citations

Neurodegenerative Diseases, Genetic Disorder, Neurology +6