Concepedia

PRP19 Transforms into a Sensor of RPA-ssDNA after DNA Damage and Drives ATR Activation via a Ubiquitin-Mediated Circuitry

Alexandre Maréchal, Ju-Mei Li, Xiao Ye Ji, Ching-Shyi Wu, Stephanie A. Yazinski, Hai Dang Nguyen, Shizhou Liu, Amanda E. Jiménez, Jianping Jin, Lee Zou

Molecular Cell · 2013 · 243 citations · 62 references

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References

62

ATM and ATR Substrate Analysis Reveals Extensive Protein Networks Responsive to DNA Damage

Shuhei Matsuoka, Bryan A. Ballif, Agata Smogorzewska et al. · Science · 2007 · 3.1K citations

, , +17

Sensing DNA Damage Through ATRIP Recognition of RPA-ssDNA Complexes

Lee Zou, Stephen J. Elledge · Science · 2003 · 2.7K citations

, , +17

Human CtIP promotes DNA end resection

Alessandro A. Sartori, Claudia Lukas, Julia Coates et al. · Nature · 2007 · 1.3K citations · Full text

, , +9

RNF8 Ubiquitylates Histones at DNA Double-Strand Breaks and Promotes Assembly of Repair Proteins

Niels Mailand, Simon Bekker‐Jensen, Helene Faustrup et al. · Cell · 2007 · 1.1K citations · Full text

, , +15

RNF8 Transduces the DNA-Damage Signal via Histone Ubiquitylation and Checkpoint Protein Assembly

Michael S.Y. Huen, Robert A. Grant, Isaac A. Manke et al. · Cell · 2007 · 1K citations · Full text

, , +16