Concepedia

Dna Damage Recognition

DNA Damage Recognition is the initial molecular process in which specific sensor proteins identify and bind to structurally altered or chemically modified sites in DNA, distinguishing them from normal DNA sequences to initiate the DNA repair cascade.

2K

Publications

175.9K

Citations

7.9K

Authors

1.6K

Institutions

Publications per year

2017–2026

335

Parents

Children

Publications

2K

CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity

Janice S. Chen, Enbo Ma, Lucas B. Harrington et al. · Science · 2018 · 4.4K citations

, , +13

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

Christopher J. Bakkenist, Michael B. Kastan · Nature · 2003 · 3.4K citations

, , +15

Sensing DNA Damage Through ATRIP Recognition of RPA-ssDNA Complexes

Lee Zou, Stephen J. Elledge · Science · 2003 · 2.7K citations

, , +17

RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO

Carsten Hoege, Boris Pfander, George‐Lucian Moldovan et al. · Nature · 2002 · 2.2K citations

, , +9

The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor

Stephan Gasser, Sandra Oršulić, Eric J. Brown et al. · Nature · 2005 · 1.3K citations · Full text

, , +16

1–5 of 2K

Authors

7.9K

  1. KS
    Kaoru Sugasawa

    Kobe University, Japan

    30 publications · 3.3K citations

    25

    h-index

  2. BV
    Bennett Van Houten

    University of Pittsburgh, United States

    28 publications · 1.8K citations

    24

    h-index

  3. FH
    Fumio Hanaoka

    The University of Osaka, Japan

    24 publications · 2.9K citations

    22

    h-index

  4. AS
    Aziz Sancar

    University of North Carolina at Chapel Hill, United States

    22 publications · 2.8K citations

    21

    h-index

  5. SI
    Shigenori Iwai

    The University of Osaka, Japan

    25 publications · 2.8K citations

    20

    h-index

1–5 of 7.9K

Institutions

1.6K

  1. Centre National de la Recherche Scientifique

    Paris, France

    45 h-index

    314 publications

    20.4K citations

  2. Harvard University

    Cambridge, United States

    44 h-index

    236 publications

    40.7K citations

  3. Massachusetts Institute of Technology

    Cambridge, United States

    41 h-index

    200 publications

    28.9K citations

  4. National Institutes of Health

    Bethesda, United States

    40 h-index

    203 publications

    28.6K citations

  5. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    38 h-index

    168 publications

    15.2K citations

  6. Howard Hughes Medical Institute

    Chevy Chase, United States

    35 h-index

    131 publications

    51K citations

  7. The University of Osaka

    Osaka, Japan

    35 h-index

    191 publications

    22.6K citations

  8. Institute of Chemical Biology and Fundamental Medicine

    Novosibirsk, Russia

    26 h-index

    179 publications

    6.3K citations

1–8 of 1.6K

Venues

  1. Journal of Biological Chemistry

    JBC · 200 publications · 17.4K citations

    77

    h-index

  2. Nucleic Acids Research

    216 publications · 12.6K citations

    66

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 85 publications · 10.4K citations

    59

    h-index

  4. Biochemistry

    117 publications · 6.2K citations

    50

    h-index

  5. Molecular Cell

    54 publications · 8.7K citations

    48

    h-index

1–5