Hai Dang Nguyen

ATR inhibition disrupts rewired homologous recombination and fork protection pathways in PARP inhibitor-resistant BRCA-deficient cancer cells

Stephanie A. Yazinski, Valentine Comaills, Rémi Buisson et al. · Genes & Development · 2017 · 386 citations · Full text

Replication Fork Protection, Genome Instability, Health Sciences +15

A mitosis-specific and R loop–driven ATR pathway promotes faithful chromosome segregation

Lilian Kabeche, Hai Dang Nguyen, Rémi Buisson et al. · Science · 2017 · 311 citations · Full text

Genetics, Molecular Genetics, Cell Cycle +22

Functions of Replication Protein A as a Sensor of R Loops and a Regulator of RNaseH1

Hai Dang Nguyen, Tribhuwan Yadav, Sumanprava Giri et al. · Molecular Cell · 2017 · 266 citations · Full text

Systems Biology, Natural Sciences, Rna Binding Proteins +7

PRP19 Transforms into a Sensor of RPA-ssDNA after DNA Damage and Drives ATR Activation via a Ubiquitin-Mediated Circuitry

Alexandre Maréchal, Ju-Mei Li, Xiao Ye Ji et al. · Molecular Cell · 2013 · 238 citations · Full text

Genome Instability, Dna Damage, Natural Sciences +9

Spliceosome Mutations Induce R Loop-Associated Sensitivity to ATR Inhibition in Myelodysplastic Syndromes

Hai Dang Nguyen, Wan Yee Leong, Weiling Li et al. · Cancer Research · 2018 · 160 citations · Full text