Concepedia

Dna Damage Sensing

DNA Damage Sensing is a molecular mechanism that constitutes the initial recognition and signaling of DNA double-strand breaks by sensor proteins, distinguishing it from downstream repair processes through its specific role in detecting genomic lesions and initiating the cellular response cascade.

732

Publications

60.7K

Citations

4.3K

Authors

1.1K

Institutions

Publications per year

2017–2026

238

Parents

Publications

732

STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors

Liufu Deng, Hua Liang, Meng Xu et al. · Immunity · 2014 · 2.1K citations · Full text

, , +17

ATM Activation by DNA Double-Strand Breaks Through the Mre11-Rad50-Nbs1 Complex

Ji‐Hoon Lee, Tanya T. Paull · Science · 2005 · 1.4K citations

, , +17

The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor

Stephan Gasser, Sandra Oršulić, Eric J. Brown et al. · Nature · 2005 · 1.3K citations · Full text

, , +16

RNF8 Transduces the DNA-Damage Signal via Histone Ubiquitylation and Checkpoint Protein Assembly

Michael S.Y. Huen, Robert A. Grant, Isaac A. Manke et al. · Cell · 2007 · 1K citations · Full text

, , +16

Structural mechanism of cytosolic DNA sensing by cGAS

Filiz Çivril, Tobias Deimling, Carina C. de Oliveira Mann et al. · Nature · 2013 · 871 citations · Full text

, , +13

1–5 of 732

Authors

4.3K

  1. MF
    Miroslav Fojta

    Czech Academy of Sciences, Institute of Biophysics, Czechia

    10 publications · 501 citations

    10

    h-index

  2. CZ
    Chun‐yang Zhang

    Shandong Normal University, China

    8 publications · 312 citations

    8

    h-index

  3. IA
    Ivan Ahel

    University of Oxford, United Kingdom

    7 publications · 752 citations

    7

    h-index

  4. SJ
    Stephen J. Elledge

    Howard Hughes Medical Institute, United States

    7 publications · 2.2K citations

    7

    h-index

  5. JM
    John M. Pascal

    Université de Montréal, Canada

    6 publications · 1.5K citations

    6

    h-index

1–5 of 4.3K

Institutions

1.1K

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    21 h-index

    50 publications

    17.4K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    20 h-index

    66 publications

    4.2K citations

  3. National Institutes of Health

    Bethesda, United States

    19 h-index

    60 publications

    5.8K citations

  4. Inserm

    Paris, France

    17 h-index

    53 publications

    5.2K citations

  5. Harvard University

    Cambridge, United States

    16 h-index

    81 publications

    13.3K citations

  6. University of Oxford

    Oxford, United Kingdom

    14 h-index

    48 publications

    3.8K citations

  7. Chinese Academy of Sciences

    Beijing, China

    14 h-index

    71 publications

    1.8K citations

  8. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    13 h-index

    63 publications

    4.5K citations

1–8 of 1.1K

Venues

  1. Nucleic Acids Research

    41 publications · 2.6K citations

    29

    h-index

  2. Journal of Biological Chemistry

    JBC · 30 publications · 1.7K citations

    25

    h-index

  3. Molecular Cell

    23 publications · 5.3K citations

    23

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 19 publications · 3.5K citations

    19

    h-index

  5. PLoS ONE

    18 publications · 703 citations

    17

    h-index

1–5