Concepedia

STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors

Liufu Deng, Hua Liang, Meng Xu, Xuanming Yang, Byron Burnette, Ainhoa Arina, Xiao-Dong Li, Helena J. Mauceri, Michael A. Beckett, Thomas E. Darga,

Immunity · 2014 · 2.1K citations · 34 references

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34

Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway

Lijun Sun, Jiaxi Wu, Fenghe Du et al. · Science · 2012 · 4.8K citations

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STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

Hiroki Ishikawa, Glen N. Barber · Nature · 2008 · 3.5K citations · Full text

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Toll-like receptor 4–dependent contribution of the immune system to anticancer chemotherapy and radiotherapy

Lionel Apétoh, François Ghiringhelli, Antoine Tesnière et al. · Nature Medicine · 2007 · 3K citations

, , +16

STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity

Hiroki Ishikawa, Zhe Ma, Glen N. Barber · Nature · 2009 · 2.7K citations · Full text

, , +14

Cyclic GMP-AMP Is an Endogenous Second Messenger in Innate Immune Signaling by Cytosolic DNA

Jiaxi Wu, Lijun Sun, Xiang Chen et al. · Science · 2012 · 2.5K citations

, , +17