Concepedia

Critical Variables affecting clinical-grade production of the self-inactivating gamma-retroviral vector for the treatment of X-linked severe combined immunodeficiency

Johannes C.M. van der Loo, William Swaney, Elke Grassman, Austen Terwilliger, Tomoyasu Higashimoto, Axel Schambach, S. Hacein-Bey-Abina, Diana Nordling, Marina Cavazzana, Adrian J. Thrasher,

Gene Therapy · 2012 · 14 citations · 19 references

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Concepts

References

19

<i>LMO2</i> -Associated Clonal T Cell Proliferation in Two Patients after Gene Therapy for SCID-X1

S. Hacein-Bey-Abina, Christof von Kalle, Manfred Schmidt et al. · Science · 2003 · 3.6K citations

, , +17

Gene Therapy of Human Severe Combined Immunodeficiency (SCID)-X1 Disease

Marina Cavazzana, Salima Hacein‐Bey, Geneviève de Saint Basile et al. · Science · 2000 · 2.6K citations

, , +17

Insertional oncogenesis in 4 patients after retrovirus-mediated gene therapy of SCID-X1

Salima Hacein‐Bey‐Abina, Alexandrine Garrigue, Gary P. Wang et al. · Journal of Clinical Investigation · 2008 · 1.8K citations · Full text

, , +14

Interleukin-2 receptor γ chain mutation results in X-linked severe combined immunodeficiency in humans

Masayuki Noguchi · Cell · 1993 · 1.3K citations

, , +10

Insertional mutagenesis combined with acquired somatic mutations causes leukemogenesis following gene therapy of SCID-X1 patients

Steven J. Howe, Marc R. Mansour, Kerstin Schwarzwaelder et al. · Journal of Clinical Investigation · 2008 · 1.3K citations · Full text

, , +13