Combined Immunodeficiency

Combined Immunodeficiency is a type of primary immunodeficiency disorder characterized by impaired development and function of both T cells and B cells, resulting in compromised adaptive immune responses.

Publications

143.3K

Citations

10.6K

Authors

2.2K

Institutions

Publications per year

2017–2026

284

Variants

CidCombined Immunodeficiencies

Parents

Pediatric Immunology

Children

Artemis DeficiencyB-cell ImmunophenotypesCd3 Complex DefectsCombined Immunodeficiency With AutoimmunityCoronin-1a DeficiencyDclre1c DeficiencyHypomorphic Gene VariantsInterleukin-2 Receptor Gamma Chain DeficiencyJak3 DeficiencyLeaky Severe Combined Immunodeficiency

Publications

<i>LMO2</i> -Associated Clonal T Cell Proliferation in Two Patients after Gene Therapy for SCID-X1

S. Hacein-Bey-Abina, Christof von Kalle, Manfred Schmidt et al. · Science · 2003 · 3.6K citations

Life Sciences, Genetics, Immunology +17

Gene Therapy of Human Severe Combined Immunodeficiency (SCID)-X1 Disease

Marina Cavazzana, Salima Hacein‐Bey, Geneviève de Saint Basile et al. · Science · 2000 · 2.6K citations

Life Sciences, Genetics, Immunology +17

A severe combined immunodeficiency mutation in the mouse

Gayle C. Bosma, R. Philip Custer, Melvin J. Bosma · Nature · 1983 · 2.2K citations

Life Sciences, Genetics, Immunology +12

T Lymphocyte-Directed Gene Therapy for ADA <sup>−</sup> SCID: Initial Trial Results After 4 Years

R. Michael Blaese, Kenneth W. Culver, A. Dusty Miller et al. · Science · 1995 · 1.5K citations

Medicine, Immunology, Molecular Medicine +16

The SCID-hu Mouse: Murine Model for the Analysis of Human Hematolymphoid Differentiation and Function

J M McCune, Reiko Namikawa, Hideto Kaneshima et al. · Science · 1988 · 1.4K citations

Life Sciences, Hematology, Immunology +17

1–5 of 2K

Authors

10.6K

JM
Jennifer M. Puck
University of California, San Francisco, United States
59 publications · 10.1K citations
43
h-index
AF
Alain Fischer
Inserm, France
54 publications · 13.7K citations
41
h-index
LD
Luigi D. Notarangelo
National Institute of Allergy and Infectious Diseases, United States
52 publications · 7.3K citations
37
h-index
RH
Rebecca H. Buckley
Duke University, United States
49 publications · 6K citations
31
h-index
MJ
Morton J. Cowan
University of California, San Francisco, United States
39 publications · 4.5K citations
31
h-index

1–5 of 10.6K

Institutions

2.2K

1–8 of 2.2K

Venues

Blood
92 publications · 9.5K citations
58
h-index
PubMed
Repository · 205 publications · 8.3K citations
44
h-index
The Journal of Immunology
JI · 86 publications · 5.8K citations
43
h-index
Journal of Allergy and Clinical Immunology
62 publications · 6.7K citations
42
h-index
Journal of Clinical Immunology
86 publications · 5.5K citations
38
h-index

1–5