Concepedia

Cd3 Complex Defects

CD3 Complex Defects is a genetic immunological disorder characterized by mutations affecting the CD3 subunits of the T-cell receptor complex, leading to impaired T-cell development and function within the context of combined immunodeficiency.

105

Publications

5.4K

Citations

570

Authors

171

Institutions

Publications per year

2017–2026

5

Parents

Publications

105

Restoration of T Cell Development in RAG-2-Deficient Mice by Functional TCR Transgenes

Yoichi Shinkai, Shigeo Koyasu, Kei-ichi Nakayama et al. · Science · 1993 · 395 citations

, , +17

Failure to synthesize the T Cell CD3-? chain: Structure and function of a partial T cell receptor complex

Jonathan Sussman · Cell · 1988 · 349 citations

, , +14

Activated macrophages induce structural abnormalities of the T cell receptor-CD3 complex.

Tomohiko Aoe, Yoshitaka Okamoto, Takashi Saito · The Journal of Experimental Medicine · 1995 · 145 citations · Full text

, , +17

Isolation and characterization of a T-lymphocyte somatic mutant with altered signal transduction by the antigen receptor.

Mark A. Goldsmith, Arthur Weiss · Proceedings of the National Academy of Sciences · 1987 · 140 citations · Full text

, , +17

Independent mutations of the human CD3–ε gene resulting in a T cell receptor/CD3 complex immunodeficiency

Claire Soudais, Jean‐Pierre de Villartay, Françoise Le Deist et al. · Nature Genetics · 1993 · 129 citations

, , +12

1–5 of 105

Authors

570

  1. JR
    José R. Regueiro

    Universidad Complutense de Madrid, Spain

    12 publications · 470 citations

    12

    h-index

  2. AA
    Antonio Arnaiz‐Villena

    Universidad Complutense de Madrid, Spain

    7 publications · 274 citations

    7

    h-index

  3. CT
    Cox Terhorst

    Harvard University, United States

    7 publications · 319 citations

    7

    h-index

  4. BA
    Balbino Alarcón

    Centro de Biología Molecular Severo Ochoa, Spain

    6 publications · 314 citations

    6

    h-index

  5. BM
    Bernard MALISSEN

    Centre d’Immunologie de Marseille-Luminy, France

    4 publications · 184 citations

    4

    h-index

1–5 of 570

Institutions

171

  1. Inserm

    Paris, France

    10 h-index

    56 publications

    3.4K citations

  2. Harvard University

    Cambridge, United States

    8 h-index

    38 publications

    1.6K citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    6 h-index

    23 publications

    577 citations

  4. Dana-Farber Cancer Institute

    Boston, United States

    6 h-index

    20 publications

    1.9K citations

  5. Universidad Complutense de Madrid

    Madrid, Spain

    6 h-index

    21 publications

    798 citations

  6. Research Institute Hospital 12 de Octubre

    Madrid, Spain

    6 h-index

    15 publications

    721 citations

  7. National Institutes of Health

    Bethesda, United States

    5 h-index

    7 publications

    385 citations

  8. Howard Hughes Medical Institute

    Chevy Chase, United States

    5 h-index

    15 publications

    1K citations

1–8 of 171

Venues

  1. The Journal of Immunology

    JI · 22 publications · 961 citations

    18

    h-index

  2. The Journal of Experimental Medicine

    8 publications · 507 citations

    8

    h-index

  3. PubMed

    Repository · 7 publications · 140 citations

    7

    h-index

  4. European Journal of Immunology

    EJI · 7 publications · 279 citations

    7

    h-index

  5. Blood

    6 publications · 207 citations

    6

    h-index

1–5