GATA4 transcription factor is required for ventral morphogenesis and heart tube formation.

Chi-Tai Kuo, Edward E. Morrisey, Roshani T. Anandappa, +5

Genes & Development

Cardiac MuscleGeneticsHeart Tube FormationNormal Cardiac MorphogenesisOrgan Development +19

Human MAIT cells are xenobiotic-resistant, tissue-targeted, CD161hi IL-17–secreting T cells

Mathilde Dusséaux, Emmanuel Martin, Nacer Serriari, +8

Blood

Antimicrobial activity of mucosal-associated invariant T cells

Lionel Le Bourhis, Emmanuel Martin, Isabelle Péguillet, +15

Nature Immunology

Mucosal ImmunologyImmunologyAntimicrobial ActivityMicrobiologyMedicine +1

Pyogenic Bacterial Infections in Humans with IRAK-4 Deficiency

Capucine Pïcard, Anne Puel, Marion Bonnet, +27

Science

Stepwise Development of MAIT Cells in Mouse and Human

Emmanuel Martin, Emmanuel Treiner, Livine Duban, +12

PLoS Biology

Impairment of immunity to <i>Candida</i> and <i>Mycobacterium</i> in humans with bi-allelic <i>RORC</i> mutations

Satoshi Okada, Janet Markle, Elissa K. Deenick, +48

Science

MAIT Cells Detect and Efficiently Lyse Bacterially-Infected Epithelial Cells

Lionel Le Bourhis, Mathilde Dusséaux, Armelle Bohineust, +12

PLoS Pathogens

Pathogenic MicrobiologyPathogen DetectionMicrobial PathogensInnate Immune SystemImmunology +21

Mucosal-associated invariant T cell alterations in obese and type 2 diabetic patients

Isabelle Magalhaes, Karine Pingris, Christine Poitou, +19

Journal of Clinical Investigation

Metabolic DisorderT-regulatory CellImmunologyPathologyDiabetic Patients +17

Inherited Interleukin-12 Deficiency: IL12B Genotype and Clinical Phenotype of 13 Patients from Six Kindreds

Capucine Pïcard, Claire Fieschi, Frédéric Altare, +21

The American Journal of Human Genetics

InflammationCytokineAllergyImmune Cell DevelopmentImmunodeficiencies +10

Targeted mutagenesis of the transcription factor GATA-4 gene in mouse embryonic stem cells disrupts visceral endoderm differentiation in vitro

Claire Soudais, Małgorzata Bielińska, Markku Heikinheimo, +6

Development