Selection of evolutionarily conserved mucosal-associated invariant T cells by MR1

Emmanuel Treiner, Livine Duban, Seiamak Bahram, +6

Nature

Mucosal ImmunologyAdaptive Immune SystemT-regulatory CellImmunologyAutoimmunity +7

Human MAIT cells are xenobiotic-resistant, tissue-targeted, CD161hi IL-17–secreting T cells

Mathilde Dusséaux, Emmanuel Martin, Nacer Serriari, +8

Blood

An Invariant T Cell Receptor α Chain Defines a Novel TAP-independent Major Histocompatibility Complex Class Ib–restricted α/β T Cell Subpopulation in Mammals

Florence Tilloy, Emmanuel Treiner, Se‐Ho Park, +6

The Journal of Experimental Medicine

HistocompatibilityAutoimmune DiseaseAlpha ChainT CellsT-regulatory Cell +12

Stepwise Development of MAIT Cells in Mouse and Human

Emmanuel Martin, Emmanuel Treiner, Livine Duban, +12

PLoS Biology

A subset of natural killer cells achieves self-tolerance without expressing inhibitory receptors specific for self-MHC molecules

Nadine Fernandez, Emmanuel Treiner, Russell E. Vance, +3

Blood

MAIT Cells Detect and Efficiently Lyse Bacterially-Infected Epithelial Cells

Lionel Le Bourhis, Mathilde Dusséaux, Armelle Bohineust, +12

PLoS Pathogens

Pathogenic MicrobiologyPathogen DetectionMicrobial PathogensInnate Immune SystemImmunology +21

Innate mucosal-associated invariant T (MAIT) cells are activated in inflammatory bowel diseases

N-E Serriari, M Eoche, L Lamotte, +9

Clinical & Experimental Immunology

Chronic Inflammatory DiseasesInnate Immune SystemImmunologyPathologyMait Cells +15

NK Cell Responsiveness Is Tuned Commensurate with the Number of Inhibitory Receptors for Self-MHC Class I: The Rheostat Model

Nathalie T. Joncker, Nadine Fernandez, Emmanuel Treiner, +2

The Journal of Immunology

ImmunologyNk CellsImmunodominanceImmunologic MechanismImmunotherapy +14

Increased tumor infiltration by mucosal-associated invariant T cells correlates with poor survival in colorectal cancer patients

Luciane Zabijak, Christophe Attencourt, Caroline Guignant, +4

Cancer Immunology Immunotherapy

Tumor InfiltrationCancer ImmunosurveillanceMedicineT-regulatory CellImmunology +7

MAIT Cells Display a Specific Response to Type 1 IFN Underlying the Adjuvant Effect of TLR7/8 Ligands

Marion Pavlovic, Christelle Gross, Chahinaize Chili, +2

Frontiers in Immunology