Concepedia

X-linked Immunodeficiency

X-Linked Immunodeficiency is a genetic disorder of the immune system characterized by mutations in genes located on the X chromosome, leading to impaired immune function predominantly in males due to the X-linked recessive inheritance pattern.

802

Publications

75.1K

Citations

4.6K

Authors

1.3K

Institutions

Publications per year

2017–2026

67

Parents

Publications

802

The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3

Craig L. Bennett, Jacinda R. Christie, Fred Ramsdell et al. · Nature Genetics · 2001 · 3.4K citations

, , +13

Gene Therapy of Human Severe Combined Immunodeficiency (SCID)-X1 Disease

Marina Cavazzana, Salima Hacein‐Bey, Geneviève de Saint Basile et al. · Science · 2000 · 2.6K citations

, , +17

Deficient expression of a B cell cytoplasmic tyrosine kinase in human X-linked agammaglobulinemia

Satoshi Tsukada, Douglas C. Saffran, David J. Rawlings et al. · Cell · 1993 · 1.3K citations

, , +17

Interleukin-2 receptor γ chain mutation results in X-linked severe combined immunodeficiency in humans

Masayuki Noguchi · Cell · 1993 · 1.3K citations

, , +10

Isolation of a novel gene mutated in Wiskott-Aldrich syndrome

Jonathan M.J. Derry, Hans D. Ochs, Uta Francke · Cell · 1994 · 1.1K citations

, , +14

1–5 of 802

Authors

4.6K

  1. HD
    Hans D. Ochs

    University of Washington, United States

    35 publications · 7K citations

    28

    h-index

  2. AF
    Alain Fischer

    Inserm, France

    28 publications · 10.5K citations

    27

    h-index

  3. JM
    Jennifer M. Puck

    University of California, San Francisco, United States

    23 publications · 2K citations

    20

    h-index

  4. GD
    Geneviève de Saint Basile

    Inserm, France

    21 publications · 6.3K citations

    20

    h-index

  5. DT
    David T. Purtilo

    University of Nebraska Medical Center, United States

    18 publications · 1.1K citations

    17

    h-index

1–5 of 4.6K

Institutions

1.3K

  1. National Institutes of Health

    Bethesda, United States

    36 h-index

    238 publications

    16.5K citations

  2. Inserm

    Paris, France

    35 h-index

    275 publications

    71.9K citations

  3. University of Washington

    Seattle, United States

    29 h-index

    112 publications

    20K citations

  4. Hôpital Necker-Enfants Malades

    Paris, France

    28 h-index

    189 publications

    45.3K citations

  5. University College London

    London, United Kingdom

    27 h-index

    139 publications

    19.2K citations

  6. University of Pennsylvania

    Philadelphia, United States

    25 h-index

    122 publications

    10.6K citations

  7. Children's Hospital of Philadelphia

    Philadelphia, United States

    25 h-index

    65 publications

    7K citations

  8. National Institute of Allergy and Infectious Diseases

    Bethesda, United States

    25 h-index

    194 publications

    17.1K citations

1–8 of 1.3K

Venues

  1. The Journal of Immunology

    JI · 63 publications · 3.7K citations

    36

    h-index

  2. PubMed

    Repository · 77 publications · 3.7K citations

    29

    h-index

  3. Blood

    30 publications · 2.9K citations

    28

    h-index

  4. The Journal of Experimental Medicine

    27 publications · 3.4K citations

    25

    h-index

  5. Clinical & Experimental Immunology

    CEI · 32 publications · 1.5K citations

    22

    h-index

1–5