Douglas C. Saffran

Deficient expression of a B cell cytoplasmic tyrosine kinase in human X-linked agammaglobulinemia

Satoshi Tsukada, Douglas C. Saffran, David J. Rawlings et al. · Cell · 1993 · 1.3K citations

Autoimmune Disease, Receptor Tyrosine Kinase, Malignant Blood Disorder +8

Mutation of Unique Region of Bruton's Tyrosine Kinase in Immunodeficient XID Mice

David J. Rawlings, Douglas C. Saffran, Satoshi Tsukada et al. · Science · 1993 · 866 citations

STEAP: A prostate-specific cell-surface antigen highly expressed in human prostate tumors

René Hubert, Igor Vivanco, Emily Chen et al. · Proceedings of the National Academy of Sciences · 1999 · 350 citations · Full text

Prostate-specific Cell-surface Antigen, Urology, Ewing Sarcoma +12

Catalytic cleavage of the androgen-regulated TMPRSS2 protease results in its secretion by prostate and prostate cancer epithelia.

Daniel Afar, Igor Vivanco, René Hubert et al. · PubMed · 2001 · 285 citations

Signal Transduction, Tmprss2-encoded Serine Protease, Medicine +14

Alternative signals to RAS for hematopoietic transformation by the BCR-ABL oncogene

Andrei Goga, Jami McLaughlin, Daniel Afar et al. · Cell · 1995 · 255 citations · Full text

Hematological Malignancy, Bcr-abl Oncogene, Signal Transduction +7