Interleukin-2 receptor γ chain mutation results in X-linked severe combined immunodeficiency in humans

Rapid and sensitive detection of point mutations and DNA polymorphisms using the polymerase chain reaction

Masato Orita, Youichi Suzuki, Takao Sekiya et al. · Genomics · 1989 · 3.5K citations

Life Sciences, Genetics, Molecular Genetics +16

Strategies for multilocus linkage analysis in humans.

G.M. Lathrop, J.-M. Lalouel, Cécile Julier et al. · Proceedings of the National Academy of Sciences · 1984 · 2.6K citations · Full text

Life Sciences, Genetics, Genomics +16

A genetic linkage map of the human genome

Cell · 1987 · 911 citations

Life Sciences, Genetics, Molecular Genetics +14

The IL-6 Signal Transducer, gp130: an Pncostatin M Receptor and Affinity Converter for the LIF Receptor

David P. Gearing, Michael R. Comeau, Della Friend et al. · Science · 1992 · 897 citations

Life Sciences, Immunology, Molecular Genetics +13

Development and function of T cells in mice rendered interleukin-2 deficient by gene targeting

Hubert Schorle, Thomas Holtschke, Thomas Hünig et al. · Nature · 1991 · 875 citations

Life Sciences, Genetics, Immunology +14